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This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
Nákup knihy
Principles of Process Research and Chemical Development in the Pharmaceutical Industry, Oljan Repic
- Jazyk
- Rok vydania
- 1998
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- Titul
- Principles of Process Research and Chemical Development in the Pharmaceutical Industry
- Jazyk
- anglicky
- Autori
- Oljan Repic
- Vydavateľ
- Wiley-Interscience
- Rok vydania
- 1998
- Väzba
- pevná
- Počet strán
- 273
- ISBN10
- 0471165166
- ISBN13
- 9780471165163
- Série
- Anotácia
- This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.