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The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.
Nákup knihy
Nongenotoxic Carcinogenesis, A. Cockburn, Lewis L. Smith
- Jazyk
- Rok vydania
- 1994
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- Titul
- Nongenotoxic Carcinogenesis
- Jazyk
- anglicky
- Autori
- A. Cockburn, Lewis L. Smith
- Vydavateľ
- Springer
- Rok vydania
- 1994
- Väzba
- pevná
- Počet strán
- 240
- ISBN10
- 3540583424
- ISBN13
- 9783540583424
- Série
- Štítky
- Veda, Medicína, Výskum, Rakovina, nádory, Biochemia, Farmakológia, Prevencia, Onkológia, Rakovina prsníka, Hormóny, Lekársky výskum, Toxikológia, Transkripcia
- Anotácia
- The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.