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Russell F. Doolittle

    Methods in Enzymology, 266
    Methods in Enzymology 183. Molecular Evolution: Computer Analysis of Protein and Nucleic Acid Sequences
    • This volume addresses a variety of areas in which computers are used to manage and manipulate nucleic acid and protein sequence data. The manipulations include searching, aligning, and determining the significance of similarities, as well as the construction of phylogenetic trees that show the evolutionary history of related sequences. Ready-to-use methods for the "at-the-bench" scientist are presented.

      Methods in Enzymology 183. Molecular Evolution: Computer Analysis of Protein and Nucleic Acid Sequences
    • Covers databases and resources; searching through databases; multiple alignment and phylogenetic trees; secondary structure considerations; and, three-dimensional considerations.

      Methods in Enzymology, 266