Richard P. Baum Knihy

The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

The narrative intertwines a detective story with character profiles and the history of science, offering a captivating exploration of a little-known chapter in astronomy. Readers will be drawn into the intriguing details and discoveries that shaped this field, making it both an engaging and educational experience.

Focusing on the advancements in nuclear medicine, this issue of PET Clinics delves into the diagnosis and treatment of neuroendocrine neoplasms, emphasizing theranostics. It explores various imaging techniques, including SPECT and PET tracers like F-DOPA and Ga-DOTA-peptides, along with Yttrium- and Lutetium-based therapies. Additionally, the role of FDG PET in managing these tumors is highlighted, providing essential insights into current practices and innovations in the field.

This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics – the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry, molecular imaging, and radionuclide therapy.