David A. Swinney Knihy

This reference addresses the pressing issue of neglected tropical diseases (NTDs) impacting over 1 billion people globally. It is the first comprehensive guide aligned with the World Health Organization's list of NTDs, authored by experts in the field. The text focuses on developing effective treatments for 12 debilitating infectious diseases that affect nearly 20% of the world's population. It covers common methodologies and critical factors influencing new drug development for these diseases. Each chapter examines a specific NTD, categorized by infectious agent—ranging from viruses to bacteria to eukaryotic parasites—highlighting the unmet medical needs and exploring current and potential drug discovery strategies. Additionally, the book discusses potential drug compounds sourced from natural products. This essential resource consolidates diverse information to foster novel treatments for NTDs, supporting WHO's initiative to eradicate these diseases. It outlines existing and prospective drugs, serving as a standard reference for the field. Targeted at medicinal and pharmaceutical chemists, virologists, parasitologists, and tropical medicine specialists, this guide is crucial for advancing successful treatments for these 12 infectious diseases.