Seid Yimer Knihy

The study focuses on the environmental impact of tannery waste, specifically from Kombolcha tannery, highlighting its detrimental effects on both people and the ecosystem. It proposes the design of an aerobic pond as a treatment solution tailored to the waste's characteristics and toxicity levels. Emphasizing the need for compliance with industrial regulations, the research advocates for cost-effective treatment methods to mitigate the negative consequences of tannery waste, aiming for a sustainable balance between industry operations and environmental health.

This bachelor thesis, graded A, presents research conducted at Bahir Dar University in the field of Chemical Engineering. It showcases the author's findings and insights into specific engineering concepts, methodologies, and applications relevant to the discipline. The work reflects a strong academic foundation and contributes to the body of knowledge in chemical engineering, emphasizing practical implications and theoretical frameworks.

Malaria disease is endemic in least developed countries like Ethiopia. The rapid development of drug-resistant malaria parasite strain leaves the need for new effective drugs. Artemisinin is a sesquiterpene lactone found in the leaves of Artemisia annua L and have different chemical structures and higher efficacy than others. The content of artemisinin is very small and from 0.5 to 1.2 % of dry weight of plants in Ethiopia. Since artemisinin is only present in the epidermis of the leaves, leaves were only washed on the outside by stirring appeared to be the most appropriate method. So the first step was solvent extraction using hexane and followed purify by repeated crystallization. Laboratory scale production data and procedures were listed for aremisinin extraction process. By using those data large scale production method was designed. And did material and energy balance calculations for large scale production process carried out by taking scientific approach followed by feasibility study. The payback period is 1.22yrs and it is economically acceptable and therefore this market is promising in Ethiopia in addition to save millions of Ethiopian and African from killer malaria.