Abul K. Abbas Knihy

Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. In print and online with additional resources, this reference is the up-to-date and readable textbook you need to master the complex subject of immunology. Access the fully searchabl

This resource offers balanced, accurate and up-to-date coverage of the core topics in human pathology. Its clinicopathologic orientation highlights the impact of molecular pathology on the practice of medicine. And, it integrates clinical and anatomic pathology, and discusses laboratory diagnosis of specific disorders.

This pocket-sized resource offers rapid, portable access to the most important facts and concepts from Robbins and Cotran Pathologic Basis of Disease, 7th Edition . It is a superb source for quick answers to clinical questions, as well as an efficient review tool on any area of the field.

In this text, a "who's who" of pathology experts delivers the most dependable, current, and complete coverage of today's essential pathology knowledge. At the same time, masterful editing and a practical organization make mastering every concept remarkably easy.

Incorporating all of the latest advances in this rapidly evolving field, two widely respected authors clearly explain how the immune system operates and describe the primary disorders that impair its function.

This book presents the proceedings from the Serono Symposia USA international symposium on Genetic Models of Immune and Inflammatory Diseases, held from October 20 to 23, 1994, in Savannah, Georgia. The introduction of gene manipulation techniques in mice, such as germline gene introduction and targeted gene disruption through homologous recombination, has equipped scientists with powerful analytical tools across various disciplines. Notably, transgenic and gene knockout technologies have significantly advanced the understanding of lymphocyte development and activation. The symposium aimed to unite researchers employing these genetic techniques to analyze the immune system, focusing on common themes and innovative directions. Transgenic mice serve numerous critical roles in immunology, allowing for the expression of defined proteins in specific tissues throughout development, thus mimicking "self" antigens. These models facilitate the investigation of immune responses to these artificially created antigens. Additionally, antigen receptors of lymphocytes can be expressed as transgenes, resulting in monospecific transgenic mice due to the unique property of allelic exclusion. Immunomodulatory agents can also be expressed in targeted tissues or throughout the body, enabling the study of the effects of dysregulated expression of biological response modifiers.