Paul M. Vanhoutte Knihy

The book serves as a comprehensive reference on the role of the endothelium in cardiovascular control, highlighting its dual ability to induce relaxation and secretion of vasoconstrictor substances. Since the landmark discovery in 1980, research has uncovered the endothelium's crucial function in monitoring blood properties and its involvement in cardiovascular diseases. This monograph aims to guide both basic scientists and practitioners by compiling essential knowledge and insights into endothelium-dependent responses, emphasizing their significance in understanding cardiovascular health.

Understanding the nature and role of endothelium-derived hyperpolarizing factor appears to be crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion and other vascular disorders. EDHF 2002 contains the proceedings of the Fourth International Symposium on endothelium-dependent hyperpolarizations and will be of interest not only to physiologists and pharmacologists puzzled by the complexity of the interactions between the endothelium and underlying vascular smooth muscle cells, but also clinical researchers and physicians treating patients with cardiovascular diseases.