Hikaru Koide Knihy

During the last few years, interest in research on the progression of chronic renal diseases has grown to the extent that this field is now in the mainstream of investigative nephrology. This interdisciplinary volume brings together the latest data from institutes at the forefront of current research. The contents cover a diverse range of topics including apoptosis in renal modeling and remodeling, the role of cytokines, growth factors and macrophages, the metabolism of interstitial collagen and collagenous materials, diabetic nephropathy, and vasoactive substances in renal injury. The use of methodology from morphometry to DNA recombinant technology illustrates the wide range of experimental approaches being adopted. Stimulating and up-to-date, this book is essential reading for nephrologists, biochemists, molecular biologists and all investigators interested in the mechanisms of renal disease progression.

This volume contains papers presented at an international symposium on the cell biology of nephron heterogeneity, which attracted leading investigators in the field. The 37 contributions are organized into five main areas of interest covering mesangium and glomerular functions, pathophysiology of the kidney, sodium, potassium and acid-base balance, signal transduction in renal cells and cell volume regulation. Taken together, they provide a comprehensive update on the progress of research for all those interested in the cellular and molecular biology of the kidney.