Biosensors

Viac o knihe

Biosensors leverage the unique properties of biological systems to selectively recognize and convert molecules, integrating the advantages of physicochemical sensor technology such as high sensitivity and ease of operation. Their development is intertwined with advances in biotechnology and microelectronics. This work presents the current state of biosensor research for specialists while also introducing fundamental concepts to lay readers. It outlines the key features of physicochemical transducer elements and biochemical recognition molecules such as enzymes, antibodies, and receptors. The text comprehensively addresses biochemical and biotechnological aspects of biomolecule immobilization and the interactions between biochemical reactions and mass transfer processes, which are crucial for effective sensor design. Detailed examples of immobilization methods are provided. The book explores the use of coupled enzyme reactions and integrated biocatalytic systems, including cell organelles and microbes, in biosensors. It covers various types of biosensors—optical, thermometric, piezoelectric, and especially electrochemical—for over 100 analytes, including immunosensors. The advantages and limitations of biosensors are discussed through examples in clinical chemistry, bioprocess control, and environmental monitoring. Finally, it examines biosensor applications in medicine, biotechnology, food industry, and environmental control,