Principles of computational cell biology

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The second edition of this essential guide for biologists and bioinformaticians has been expanded and improved. Originally published in 2008, it introduced a network-based approach to studying cellular systems. The revised edition emphasizes RNA biology and epigenetics, and introduces new topics such as intracellular trafficking, circadian rhythms, apoptosis, and cell differentiation. Author Volkhard Helms, an expert in biology and informatics, presents the key points in an accessible manner, including problems and exercises for each chapter to demonstrate the application of concepts and methods. While introducing complex aspects of the subject, the book minimizes mathematical content. This important guide continues the success of its predecessor by teaching a network-based approach to cell biology, covering new topics like microRNAs, epigenetics, and protein-DNA interactions. It includes problems and solution hints for each chapter and emphasizes practical aspects of cellular biology. Targeted at biology students, biochemistry students, cell biologists, biomathematicians, biochemists, and bioengineers, this revised edition serves as an ideal introduction to modeling biological processes at the cellular level.