The Biology of Cancer

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Thoroughly updated to reflect significant advances in cancer biology, this textbook remains a favorite among students, instructors, researchers, and clinicians globally. It serves as a comprehensive resource for those studying the molecular and cellular bases of cancer at various educational levels. The principles of cancer biology are presented clearly and in-depth, enhanced by an extensive full-color art program and numerous pedagogical features that make the content engaging and accessible. Key experiments are highlighted to foster a sense of discovery and provide insights into the foundational concepts of modern cancer biology. The revised edition incorporates major developments from the past six years, including updates on the tumor microenvironment, metastatic dissemination, tumor immunology, cancer stem cells, the epithelial-mesenchymal transition, multi-step tumorigenesis, invasion and metastasis, cancer cell genome mutations, traditional therapy, epigenetic contributions, microRNA involvement, and the Warburg effect. Beyond its textbook value, it serves as a valuable reference for biomedical professionals. Each copy includes an updated "Pathways in Human Cancer" poster and a DVD-ROM featuring the art program, movies, audio mini-lectures, Supplementary Sidebars, and a Media Guide.